MotifFinder

Antibody-Extractor Suite

MotifFinder searches for motifs in Frameworks and CDRs.

Features

For every motif, AA position, feature (FW or CDR) and Solvent Accessibility are displayed. Selected chains are exported or reprocessed with other Antibody-Extractor tools.

Scenarios

Scenario 1

Antibody discovery team wants to check if there is in their antibody collection a potential candidate for intracellular delivery.

MotifFinder screens the 1200 VH sequence for Endosomal Escape Domains (EED) and extracts the VH chains with EED. MotifFinder determines in which feature, Frameworks or CDRs the EED are found.